|
KMID : 0032220210330050467
|
|
Annals of Dermatology
2021 Volume.33 No. 5 p.467 ~ p.469
|
|
|
A Case of Newly Developed Pemphigus Foliaceus and Possible Association with Alternative Bee-Venom Therapy
|
|
Yoo Seung-Ah
Park Hyo-Eun
Kim Mi-Ri
|
|
|
Abstract
|
|
|
|
Bee-venom is composed of a variety of peptides, enzymes, and biogenic amines, and is demonstrated to have both antiinflammatory and immune-stimulatory effects in human body. Pemphigus foliaceus (PF) is a variant of pemphigus, which is a rare autoimmune bullous disease presenting with erythematous scaly crusted plaques. Although the exact pathogenesis was not identified, there have been three case reports of autoimmune disorders associated with bee-venom. In this case, a 64-year-old female was diagnosed with PF, which was developed after alternative bee-venom acupuncture therapy. We assumed that the bee-venom caused the diseases through a temporal relationship and its known immunostimulatory action. Herein, we suggest that physicians recognize the possibility of bee-venom stimulating the immune system and triggering various autoimmune diseases including pemphigus.
|
|
|
KEYWORD
|
|
|
Autoimmune diseases, Bee venoms, Immunology, Pemphigus
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|